Where and when: Marvel Stadium, Sunday May 5, 1.10pm AEST
Last time they met: Blundstone Arena, round four, 2018: North Melbourne 18.8 (116) defeated Carlton 4.6 (30)
This one was virtually over as soon as it started. The Roos controlled the match from the get-go in Hobart, with Ben Brown kicking five majors on their way to an 86-point win. Shaun Higgins racked up 35 touches.
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What it means for Carlton: After yet another 'honourable loss' last weekend, the Blues again must keep their focus simple: It's all about getting over the line for Carlton.
What it means for North Melbourne: The Roos' season is hanging by a thread. After an improved performance against the Power, this could be their last chance to salvage something from 2019.
How Carlton wins: By taking its chances. Having thrown away a 36-point lead against Hawthorn, Carlton knows it has the cattle to win on Sunday; although the loss of key players to injury (Simpson, McGovern, Newman, Kreuzer) will hurt. Will a more consistent effort over four quarters be enough?
How North Melbourne wins: By re-finding its mojo. Rewind back to last year and North Melbourne produced an emphatic performance to beat Carlton. That type of footy will again secure the points on Sunday.
The stat: History suggestas not to expect a close game. Three of the last four meetings between Carlton and North Melbourne have been decided by more than 10 goals. But this one will surely be tighter.
The match-up: Harry McKay v Robbie Tarrant
McKay remains one of the game's in-form key forwards, clunking another six marks and kicking two goals on Sunday. The task of stopping him falls at the feet of Tarrant, and successfully doing so could prove crucial to North Melbourne's chances.
It's a big week for: Ben Brown (North Melbourne)
Having already come in for some criticism this season, Brown was held goalless for the first time this year on Friday night. He was easily best on ground the last time these two sides met and will be hoping to rectify his form slump on Sunday.
Can Ben Brown bounce back against the Blues? Picture: AFL Photos
Big call: Brown stutters again, but Roos still prove too good
Prediction: North Melbourne by 11 points