"We thank Nick, George, Jordan, Jackson and Jesse for their contributions to the club and wish them every success," Geelong football manager Neil Balme said.
"It is never easy letting players go, but we hope they receive opportunity at other clubs in the future.
"George, Jordan, Jackson and Jesse all received opportunity at AFL level and played in our 2012 VFL premiership."
Josh Cowan and James Toohey have had their contracts extended, while the Cats have upgraded ruckman Mark Blicavs from their rookie list to their senior list.
"Mark has shown incredible improvement since first joining us in 2012 and has been a very good contributor to our team in the past two years," Balme said.
"We believe he still has significant upside and will be able to play a variety of roles."