PORT Adelaide will be without key forward Charlie Dixon for the rest of season after he sustained a serious ankle injury in the Power's heartbreaking four-point loss to West Coast at Adelaide Oval on Saturday.

Star ruckman Paddy Ryder (hip flexor) and defender Dan Houston (concussion) are also in doubt for next week's huge game with Collingwood at the MCG after failing to finish the game.

Dixon came off worse for wear after a marking contest with Eagles defender Tom Barrass in the third quarter.

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Dixon landed awkwardly on his ankle and was helped off the ground by trainers.

"Dixon won't play again this year, he's got a badly sprained, possibly broken ankle," Power coach Ken Hinkley said.

"You saw the way it happened.

"People will imagine it was a flimsy ankle, but that's not the issue, that's just a collision injury.

"He'll be fine, he'll get over it and he'll get on with it, and he'll recover, if that's what it takes.

"From our point of view, it's a smooth recovery, but he won't play again this year."

Ryder first injured his hip flexor in the round 17 loss to Fremantle and was originally expected to be sidelined for a month. Instead, he missed just one game and returned for the round 19 win against the Western Bulldogs.

He rucked strongly in the first half against the Eagles and kicked a goal to put the Power up by 28 points in the third quarter before coming from the ground.

"Ryder aggravated his hip flexor, he's still some chance because we took the cautious approach, because we know where we're at in the season," Hinkley said.

Houston left the ground on a medicab after a big collision with Eagles midfielder Brendon Ah Chee when both players attacked the ball.

Play was stopped for several minutes and he was later taken to hospital by ambulance.

"He's had some precautionary x-rays and stuff, but I think he'll be fine. He copped a big hit and unless there's anything we haven't seen yet, we expect he will be okay," Hinkley said.

"I haven't heard from the doctors regarding concussion, but it was more, the hit took a lot out of him.

"He got hit in the chest and neck, so whether he's hit his head on the ground as well, he's been to hospital to get some checks done on that."

The Power played the final term with only 19 fit men and were overrun with Jeremy McGovern kicking a goal after the siren to seal an incredible victory.

The collision that left Dan Houston with a concussion. Picture: AFL Photos