Where and when: Giants Stadium, Sunday July 7, 4.40pm AEST
TV, radio and online: Click here for broadcast guide
What it means for GWS: After last week's poor finish against Essendon cost them a vital win, the Giants must respond against a fellow top-eight contender with four quarters of intense, contested footy.
What it means for Brisbane: A big scalp away from the Gabba would be massive for the Lions' confidence and let the rest of the competition know they're the real deal and ready for a long-awaited finals berth.
The stat: The Giants conversion (47.6 per cent) in front of goal cost them dearly last week against the Bombers, who went at 70.6 per cent. The home side must nail their chances against Brisbane at Giants Stadium.
The match-up: Shane Mumford v Stefan Martin
Mumford has copped some criticism in recent weeks for his free kicks against tally, but he's still a massive part of the Giants' midfield. Martin will match Mumford's aggression at the contest and will try and exploit him around the ground, especially late in quarters.
It’s a big week for: Jeremy Cameron
Facing the Lions for the first time since he was suspended for a brutal hit on defender Harris Andrews, the Coleman Medal leader will want to have an impact. With just five goals from his past three games, the athletic forward is due for a big haul.
Big call: Cameron, Harry Himmelberg and Jeremy Finlayson laid just four tackles between them last week against the Bombers, a damning stat. The trio will respond this week with at least five apiece, and they'll add 10 goals between them.
Prediction: GWS by 25 points