Bombers chairman David Evans released a statement on Wednesday night, in response to a story in the Herald Sun.
"Contrary to media reports, the Essendon Football Club has never conceded that our players have been given banned substances in 2012," Evans' statement said.
"We asked for the ASADA investigation, and out of respect to the players, those investigations must be completed without prejudice.
"I want to repeat, our club has not conceded that our players have been given banned substances in 2012.
"At all times, our board's primary goal has been to look after the interests of our players.
"On behalf of our members, I want to thank our players for the leadership and resilience they are showing under pressure.
"They are young men of great character and continue to display their commitment to our club."
Earlier on Wednesday the Bombers confirmed the release of the independent review into the club's governance and practices by Dr Ziggy Switkowski had been delayed by a legal issue.
The findings of the review were slated to be released on Tuesday.
ASADA's investigation into Essendon's 2012 supplements program continues.