The League has announced that the clashes between Melbourne and St Kilda at Casey Fields, Geelong and North Melbourne at Simonds Stadium, and Fremantle and the Western Bulldogs in Mandurah, south of Perth – all on Saturday afternoon – will be played under changed conditions due to heat.
Saturday night's NAB Cup 'preliminary final' between Collingwood and the Brisbane Lions at Etihad Stadium on Saturday night will also be subject to the changes.
In each match, the cap of 80 interchange rotations will not apply, and clubs will be allowed to use six interchange players, rather than three interchange and three substitutes.
Melbourne's weather is forecast to reach 34 degrees on Saturday, with Geelong expected to hit 35 and Mandurah 31.
It has already been announced that Saturday night's Port Adelaide versus West Coast match will have shortened quarters and extended break times, with a decision on interchange rules to be made closer to the start.
After Carlton's loss to Adelaide on Friday night, the Kangaroos can secure a place in the pre-season Grand Final by beating the Cats.
The winner of the match between the Magpies and Lions will also be guaranteed a place in next week's decider..