Physical performance manager Brett Burton confirmed on Tuesday the Lions would undertake more aerobic training ahead of next season's limit of 120 rotations per match.
The AFL Commission has approved the cap for the next two seasons.
The Lions will start pre-season training in early November with a two-week altitude camp in Arizona.
Burton said the Lions had been forced to re-think their approach after last month's decision.
"With the interchange cap next year, we know the game will become a bit more aerobic, so that lends itself to the program being more aerobic and a little less repeat speed, high intensity," Burton said.
"You're looking for that one per cent improvement, and whether you do that through research or having a look at other elite teams around the globe, you're looking for an improvement and where you can get it."
The Lions will send their five-year plus players to Arizona – around 25 in all.
They sent a senior group of five players to Arizona in 2011, and then took 15 over last year.
Burton said although there were numerous physiological benefits of training in thinner air, the psychological boost was equally important.
"We know our guys enjoy getting away from the environment here," he said.
"Some guys have been training for 10-12 years in this environment, so to take them out of there and take them overseas has a sizeable psychological advantage.
"Those 25 guys will come back into the program and only have two weeks of training before Christmas.
"You tell any guy they've got two weeks of training before Christmas, they'll think that's amazing.
"We're trying to achieve the same kind of conditioning benefit they'd receive here, but less loading on the joints."
Veterans Simon Black and Jonathan Brown have yet to decide on their futures after undergoing respective surgeries in the past month.
Twitter: @AFL_mikewhiting
