The 2008 All-Australian, who returned to the Suns line-up last week after over a year on the sidelines with a broken leg, was forced from the ground just before half-time in Gold Coast's 13-point victory over Melbourne at Metricon Stadium.
The Suns confirmed Bock will undergo surgery to remove a rod and will play no further part in their season.
Starting again at Metricon after kicking two goals in his return against the Eagles, Bock never looked comfortable and spent the second half icing his leg.
"We were trying to get him through to next week but he's very ginger and sore," Suns coach Guy McKenna said after the game.
"We'll book him into the surgeon and get a nasty rod out which will be good.
"It's sad that he can't finish the year off but good in his progression for next year."
Perhaps more worrying for the Suns is the injury to Alex Sexton, who in just his fourth game of the season left the ground clutching his shoulder after a melee in the final quarter.
He was rushed to hospital for treatment on the dislocation of his AC joint, which is almost certain to also end his campaign.
McKenna will be forced to find at least one more replacement for next Saturday's trip to Port Adelaide as Sam Day also finished the match on the bench with a tight hamstring.
The coach admitted "he is likely a no-show for next week".
One pleasing note on the injury front for McKenna's improving side is the fine form of David Swallow, playing in midfield in his second match back after being sidelined with a knee injury.
With Gary Ablett being limited to 19 touches in his milestone 250th game, Swallow stood tall with 28 possessions in a best-on-ground performance.
"He's played a lot of super games," McKenna said.
"He played a special game down in Melbourne at half-back coming off injury. We didn't have a lot of defenders (and) he gave us some drive and run at the MCG.
"Because of injuries he went more wing and on-ball this week.
"(It is) just his attack on the ball, he's done that since he was a 16-year-old when he joined us.
"He was super in the VFL and his first three years (in the AFL) have been super as well."
