Petrie has booted 25 goals in his past eight matches to be a key player in the Kangaroos' mid-season surge into top-eight contention.
Blues coach Brett Ratten said on Wednesday that shutting down Petrie's marking power would be a key to winning.
With full-back Michael Jamison still absent with a knee injury, Henderson shapes as the most likely match-up for the dangerous forward.
"If I get him, it'll be a good challenge for me," the 21 year-old said from Etihad Stadium on Thursday morning after the Blues had a light training run at the ground.
"He's in red-hot form.
"He's a very good one-on-one player and he's really straightening them up."
The former Brisbane Lion - known mainly as a forward during his short AFL career so far - said he had enjoyed his time in defence, but would be happy to play wherever he was needed once Jamison returned as long as it meant holding his spot.
"It's a bit different having to follow someone else around; I'm usually able to just run free," Henderson said.
"But it's nice…and I'm really enjoying the challenge.
"I've just got to keep performing well week-to-week and then they can't throw me out [of the team].
"Hopefully [once Jamison comes back] I can maybe slot back forward or slot into that second defender's role.
"We'll just have to see what happens."
