Ed Barlow and Matt O'Dwyer have both been axed, the pair joining Kristin Thornton as Swans looking for a chance in the pre-season or rookie drafts after failing to win a new contract.
Barlow, a 2006 rookie draft selection, played 26 games for the Swans and kicked 18 goals.
O’Dwyer, who was a 2007 rookie draft selection, played seven matches.
The Swans will make a minimum of six changes to their senior list in 2011.
Along with the delistings, Brett Kirk and Henry Playfair have retired, while youngster Patrick Veszpremi was traded to the Western Bulldogs earlier this month.
Two rookies - Jake Orreal and Taylor Gilchrist - have also been delisted.
The Swans' first pick in next month's draft comes at selection No.21.
