GREATER Western Sydney midfielder Ryan Griffen will miss the Giants' final match against Melbourne after scans revealed the veteran has a grade-two medial ligament injury.

Griffen, who hasn't missed a game this season, suffered the injury to his right knee in the third term of the Giants' 81-point win over Carlton at Spotless Stadium on Saturday.

The 29-year-old won't require surgery and is expected to be available for the beginning of pre-season training in November.

In more positive news for coach Leon Cameron, defender Nick Haynes is a chance to return this week after missing the clash with the Blues due to groin soreness.

Ruckman Andrew Phillips will likely miss another week with a shoulder injury but will be available for the NEAFL finals the following week.

Meanwhile, rookie-listed midfielder Sam Schulz ruptured his anterior cruciate ligament during Saturday’s NEAFL match against Sydney University at Spotless Stadium.

The 22-year-old, one of the first players signed to the Giants, will meet with a knee specialist on Monday afternoon.