THE AFL's most senior female executive, Dorothy Hisgrove, has quit the League after two years in her role as general manager of people, customer and community.

Hisgrove was appointed to the AFL executive in April 2013, with responsibilities overseeing the human resources roles within the League as well as broader club and community programs.

She had come to the AFL after stints with Australia Post, NAB, AXA Asia Pacific and BHP Billiton.

But on Monday AFL chief executive Gillon McLachlan announced Hisgrove had resigned from her role, saying she had been a highly valued member of the executive.

"Under her leadership, we have grown the kids segment including an increase in junior community club numbers. In our developing markets of NSW and Queensland we have also seen growth in AFL kids membership," McLachlan said in a statement.

"Dorothy has also played a lead role in evolving from the traditional women's round to a broader strategic focus to improve gender diversity across our industry.

"Dorothy's wealth of experience from the corporate sector was a significant asset to the AFL over the past two years and we thank her for her commitment and the energy she brought to the organisation."

Hisgrove will remain involved with the AFL on a consultative basis with regards to leadership development and other diversity projects.