Having started with just one win from their opening five games, the Eagles have now won four straight, capped by a 23.17 (155) to 8.7 (55) triumph over the Giants in front of 6324 fans at Skoda Stadium.
With Dean Brogan (back) a late GWS withdrawal, Nic Naitanui and Dean Cox tormented Jonathan Giles in the ruck, while the West Coast forwards also had a field day.
Jack Darling (five goals), Josh Kennedy (five), Mark LeCras (three) and Josh Hill (three) all benefited from some silver service, while Chris Masten, Luke Shuey, Andrew Gaff and Matt Priddis led a dominant midfield performance.
Five talking points: Giants v Eagles
"We are really satisfied with the way we came and performed today," West Coast coach John Worsfold said.
"Our focus was to come and perform well for four quarters and I think the boys did that."
Click here to vote for the three best West Coast players from this game
It was another day of development for the young Giants, who tackle Carlton next week still searching for their first win of the year.
Jeremy Cameron continues to amaze, managing another three goals from limited opportunities to take his tally for the year to 25.
There were also flashes of the side the Giants will eventually become, particularly in a competitive third term, which finished four goals apiece.
But an overall hit-out count of 55-23 in West Coast's favour and 52-34 in the clearances made it a straightforward day for the West Australian club.
"If someone had sneezed at that end it might've been a goal and we might've won the quarter," GWS coach Kevin Sheedy said of a close call just before three quarter-time.
"Very rarely do we get that opportunity to win a quarter against West Coast, who are a damn good side.
"Look at the hitouts compared to ours. We're basically off the back foot right from the start."
Click here to vote for the three best GWS players from this game
Tom Scully, Lachie Whitfield, Toby Greene and Adam Treloar had their moments through the middle of the ground, but it was an otherwise predictable result between two teams with opposite ambitions in 2013.
The game got off to a cagey start, with scores locked at 1.1 after 10 minutes, before five Eagle goals in a 13-minute span broke the contest open.
Bradd Dalziell is collected by his teammate Josh Kennedy. Picture: AFL Media
A late Sam Butler snap gave West Coast a 33-point lead at the first change.
The Eagles then pressed home their advantage in the second quarter, doubling its lead to 66 points at half-time.
It was then relatively comfortable the rest of the way for the visitors, who host Richmond at Patersons Stadium next week.
GREATER WESTERN SYDNEY 2.1 4.3 8.3 8.7 (55)
WEST COAST 7.4 14.9 18.12 23.15 (155)
GOALS
Greater Western Sydney: Cameron 3, Ward 2, Smith, Scully, O'hAilpin
West Coast: Darling, Kennedy 5, Le Cras, Hill 3, Naitanui 2, Shuey, Sheppard, Kerr, Gaff, Butler
BEST
Greater Western Sydney: Cameron, Greene, Scully, Whitfield, Ward
West Coast: Naitanui, Darling, Kennedy, Priddis, Gaff, Hurn, Masten
INJURIES
Greater Western Sydney: Dean Brogan (back spasms) replaced in the selected side by Setanta O'hAilpin
West Coast: Bradd Dalziell (concussion)
SUBSTITUTES
Greater Western Sydney: Setanta O'hAilpin replaced by Curtly Hampton at half time
West Coast: Bradd Dalziell replaced by Mark Hutchings at quarter time
Reports: Nil
Umpires: Stewart, Fila, Burgess
Official crowd: 6,324 at Skoda Stadium
James Dampney is a reporter for AFL.com.au. Follow him on Twitter: @AFL_JD