ELIZA James' last-gasp goal has secured Collingwood a two-point win over St Kilda at RSEA Park.

The Saints nearly pulled off a massive upset on Saturday, but the third-placed Magpies held them off in a fierce duel to win 4.12 (36) to 5.4 (34).

James celebrated her 19th birthday with a superb snap from an acute angle that bounced through, giving the Magpies the lead.

04:27

Last two mins: Teenage Pie kicks last-minute goal to break Saints' hearts

The thrilling final moments between the Saints and the Magpies in S7 round six

They held on grimly in a frantic last minute to register their fifth win of the season.

"I just threw it on the boot and watched it ... I was pretty lucky," James told Channel Seven after the match.

SAINTS v MAGPIES Full match coverage and stats

Trailing by six points at the last change, the Saints kicked two goals and took a seven-point lead.

Nicola Stevens should have sealed the win with three minutes remaining, but she missed on the run from point-black range.

05:30

AFLW S7 Highlights: St Kilda v Collingwood

The Saints and Pies clash in round six of the 2022 NAB AFL Women's Competition

That left the door open for the Magpies and set the scene for James' match-winner.

The Saints out-pressured Collingwood with 73 tackles to 60, but the Magpies had more poise and they held their nerve.

St Kilda's Hannah Stuart was best afield with 25 disposals and two goals, while their key-position player Kate Shierlaw kicked a goal in the last term and was mighty with her marking and pressure.

Collingwood's Jaimee Lambert gathered 21 disposals, while teammate Ruby Schleicher had 20.

00:38

Stuart's sizzler gives Saints back the lead

Hannah Stuart nails her second major of the afternoon with this incredible snapping finish during the second term

Up next
St Kilda returns to RSEA Park next Friday night to take on Carlton, while Collingwood will look to consolidate a spot in the top four against the Giants in the late game at Victoria Park on Sunday.

ST KILDA      2.0     3.2     3.2     5.4      (34)
COLLINGWOOD                2.4     2.7     3.8    4.12    (36)

GOALS
St Kilda: Stuart 2, Stevens, Matin, Shierlaw
Collingwood: Lin, Brazill, Rowe, James

BEST
St Kilda: Stuart, Patrikios, Dillon, Xenos, McDonald, Stevens
Collingwood: Lambert, Schleicher, Cann, Brazill, Allen

INJURIES
St Kilda: Guttridge (foot)
Collingwood: Nil

LATE CHANGES
St Kilda: Olivia Vesely (rested) replaced in selected side by Deanna Jolliffe
Collingwood: Nil

Reports: Nil