THE WESTERN Bulldogs will be looking to start a new chapter when they take on Greater Western Sydney at Manuka Oval on Saturday.
No.1 draft pick Kristie-Lee Weston-Turner will debut for the Dogs alongside three other draftees, while the Giants will be hoping to celebrate Alyce Parker's 50th AFLW match with a win.
GIANTS v BULLDOGS Full match coverage and stats
Once the action in Canberra wraps up, attention turns to Windy Hill where Essendon hosts Fremantle.
Three Dockers recruits in Gabby Newton, Ash Brazill and Aisling McCarthy will run out in the purple guernsey for the first time, while the Bombers will be looking to back up last year's finals appearance with another strong season.
BOMBERS v DOCKERS Full match coverage and stats
Gold Coast then hosts St Kilda up north, where second-year Saint Serene Watson will face her former side.
The Suns' defensive stocks have been boosted by off-season acquisitions Katie Lynch and Charlotte Wilson, who will run out in their new colours for the first time.
SUNS v SAINTS Full match coverage and stats
The evening session kicks off with Geelong and Melbourne facing off at GMHBA Stadium.
The Cats defied all expectations last year, sending the Demons packing in their semi-final to advance to the preliminary final.
After that embarrassing straight-sets exit, the season seven premiers will have an axe to grind, but the Cats are more than equipped to handle it.
CATS v DEMONS Full match coverage and stats
The best has been saved until last, with Port Adelaide and Adelaide to take to the field in the AFLW Showdown at 7.15pm ACST on Saturday.
The SA rivalry has well and truly carried over into the women's competition, with the Power to don their controversial prison bar guernsey for the first time in the AFLW.
POWER v CROWS Full match coverage and stats