CARLTON has suffered a massive blow with skipper Marc Murphy withdrawing from the side to face North Melbourne at Blundstone Arena.
Murphy injured his left foot in the warm-up and struggled to put any weight on it.
Carlton football manager Andrew McKay confirmed he aggravated a plantar fascia problem and he will have scans next week.
The Blues made the call to replace him five minutes before the opening bounce.
Nick Graham came in as his replacement.
The Roos are unchanged.
West Coast v Gold Coast at Optus Stadium, 6.10pm AWST
NO LATE CHANGES
FINAL INTERCHANGES
West Coast: Jack Redden, Daniel Venables, Jackson Nelson, Jake Waterman
Gold Coast: Jack Martin, Brayden Fiorini, Michael Rischitelli, Darcy MacPherson
North Melbourne v Carlton at Blundstone Arena, 7.25pm AEST
LATE CHANGES
North Melbourne: Nil
Carlton: Marc Murphy (foot) replaced in selected side by Nick Graham
FINAL INTERCHANGES
North Melbourne: Luke Davies-Uniacke, Jy Simpkin, Ed Vickers-Willis, Billy Hartung
Carlton: Jack Silvagni, Paddy Dow, Jarrod Garlett, Cam O'Shea
Western Bulldogs v Sydney at Etihad Stadium, 4.35pm AEST
NO LATE CHANGES
FINAL INTERCHANGES
Western Bulldogs: Mitch Honeychurch, Shane Biggs, Caleb Daniel, Lin Jong
Sydney: Oliver Florent, Dean Towers, Nic Newman, Aliir Aliir
Follow it LIVE: Bulldogs v Swans
Richmond v Brisbane at the MCG, 2.10pm AEST
NO LATE CHANGES
FINAL INTERCHANGES
Richmond: Dion Prestia, Shaun Grigg, Bachar Houli, Jacob Townsend
Brisbane: Jarrod Berry, Alex Witherden, Zac Bailey, Rhys Mathieson
Follow it LIVE: Tigers v Lions
Greater Western Sydney v Fremantle at UNSW Canberra Oval, 1.45pm AEST
LATE CHANGES
GWS: Nil
Fremantle: Ed Langdon (illness) replaced in the selected side by Darcy Tucker
FINAL INTERCHANGES
GWS: Jacob Hopper, Matt de Boer, Harry Himmelberg, Sam Reid
Fremantle: Adam Cerra, Andrew Brayshaw, Connor Blakely, Cam McCarthy
Follow it LIVE: Giants v Dockers