Dangerfield, who has held the title for the past three years, has decided not to participate this year, with All Australian teammate Brodie Smith chosen as his replacement.
Geelong's Jordan Murdoch is likely to start as favourite for the event this year, having posted one of the fastest ever 20m sprint times at the AFL Combine – stopping the clock at 2.86 seconds.
Murdoch's run and carry ability has been evident in his football this season.
Hawk Billy Hartung and fellow youngster Ben Kennedy from Collingwood are also likely to be in the mix, while Demon Jayden Hunt has a reputation for being quick.
West Coast's Will Schofield and the Western Bulldogs Jason Tutt are others who should feature prominently.
The heats for the event will be held at 12.30pm ahead of the start of the Hawthorn-Sydney Swans game, with the final of the sprint to be run during the half-time break, at approximately 3.40pm.
2014 Grand Final Sprint participants
Adelaide Brodie Smith
Brisbane Lions Daniel McStay
Carlton Kane Lucas
Collingwood Ben Kennedy
Essendon Patrick Ambrose
Fremantle Zac Dawson
Geelong Jordan Murdoch
GWS Adam Tomlinson
Hawthorn Billy Hartung
Melbourne Jayden Hunt
North Melbourne Luke McDonald
Richmond Bachar Houli
St Kilda Clint Jones
Sydney Swans Daniel Robinson
West Coast Will Schofield
Western Bulldogs Jason Tutt