Dank said he would never endanger anyone with the substances he administers through his work.
The former Essendon sports scientist is at the centre of doping investigations that have rocked the AFL and NRL.
Dank has also alleged he injected Bombers coach James Hird with hexarelin - a growth hormone-releasing substance not banned for coaches.
E-mails reveal Hird's supplement guidelines
Hird is now under growing pressure to stand down pending the results of investigations into Essendon.
Demetriou said on Thursday he was horrified at some of the substances allegedly involved last year in Essendon's supplement program, which Dank oversaw.
Hird is now under growing pressure to stand down pending the results of investigations into Essendon.
Demetriou said on Thursday he was horrified at some of the substances allegedly involved last year in Essendon's supplement program, which Dank oversaw.
Hird says he won't be stepping down
But Dank dismissed Demetriou's concerns in a statement given to Channel Nine, saying the AFL boss was "way out of line" and "should pull his head in".
"He should be very careful about the comments he's making publicly," Dank said.
"He has never identified any substance as being, to use his words, 'injurious'.
"I challenge him to do that."
But Dank dismissed Demetriou's concerns in a statement given to Channel Nine, saying the AFL boss was "way out of line" and "should pull his head in".
"He should be very careful about the comments he's making publicly," Dank said.
"He has never identified any substance as being, to use his words, 'injurious'.
"I challenge him to do that."
Hird-Dank text messages revealed
Dank added the last time he checked, Demetriou had no medical or scientific background.
The sports scientist also had mixed feelings about Hird, saying the Bombers coach had done nothing wrong.
Dank added the last time he checked, Demetriou had no medical or scientific background.
The sports scientist also had mixed feelings about Hird, saying the Bombers coach had done nothing wrong.
Drug allegations very disturbing: Demetriou
But he added it was not his place to comment on Hird's reaction to the crisis.
"I know he has done nothing wrong as far as the supplement program goes - he should not be sacked for his part in that," Dank said.
"As for the way he's handled himself in recent times, that is for others to judge.
"It is perhaps understandable that his reaction is a product of fear and ignorance generated by the way authorities have mishandled the investigation."
