THE AFL will bolster its integrity unit and review its anti-doping code as it seeks to combat the growing dangers of banned substances in Australian sport.

In response to a damning report into organised crime and drugs in sport released by the Australian Crime Commission (ACC) on Thursday, League CEO Andrew Demetriou said his administration would carefully examine the document's findings and "initiate investigations as required".

"Under the World Anti-Doping Authority code, it is very clear the use of performance-enhancing drugs has no place in sport, and obviously we support that principle," Demetriou said.

"I urge any current or former player or club official with knowledge of inappropriate behaviour or activity to come forward and assist our efforts.

"Plans are also underway for the AFL to add to its integrity capabilities in the coming weeks so we remain at the forefront of efforts in Australian sport to combat corruption risks."

Demetriou said the AFL would also meet with its clubs to review levels of medical supervision over fitness and conditioning programs.

The report comes at a crucial time for the competition, which has been rocked by revelations earlier this week that Essendon players may have been supplied with banned supplements during the 2012 season.

The Bombers came forward on Tuesday, initiating an investigation to be conducted by the AFL and the Australian Sports Anti-Doping Authority.

Demetriou said the League had been proactive in seeking to protect the integrity of the game, instituting its integrity unit in 2008 to police match-fixing, doping, gambling and other integrity issues.

He urged legislative action to allow greater information sharing between investigative authorities and sports bodies.

"The AFL is devoting significant resources to our integrity capabilities and also providing education to AFL players and officials about the risks associated with performance-enhancing drugs and the consequences of involvement in any form of match-fixing activity," Demetriou said.

The ACC report, which took 12 months to compile, found widespread use of performance enhancing druges, including peptides and hormones, in multiple sports, and links between athletes and organised crime.