Trengove was suspended after a tackle on Adelaide's Patrick Dangerfield left the Crow concussed and unable to play on in last Sunday's encounter.
Dangerfield was immediately substituted off.
Melbourne has appealed the suspension on three grounds: that the decision was so unreasonable that no tribunal could have come to that decision having regard to the evidence; that the classification of the level of the offence was manifestly excessive, and that the sanction imposed was manifestly excessive.
Trengove was initially suspended for two weeks by the match review panel but the sanction was compounded when he unsuccessfully challenged it at the tribunal on Tuesday night.
The Demons had called expert witnesses Kelly O'Donnell, the club's tackling coach, and bio-mechanist Dr Kevin Ball as part of their unsuccessful defence.
Tribunal counsel Andrew Tinney SC argued that by grabbing Dangerfield's arm and keeping hold of it throughout the tackle Trengove had not exercised his duty of care to his fellow player's safety.
Tribunal members Emmett Dunne, Wayne Henwood and Wayne Schimmelbusch dismissed the Melbourne legal team's challenge, leading to an outpouring of sympathy from Trengove's teammates.
A number of Melbourne players vented their frustration via Twitter.
Brad Green, James Frawley, Colin Sylvia, Luke Tapscott, Cale Morton, Nathan Jones and Jack Watts all voiced their disapproval of the decision, but football operations manager Adrian Anderson told Triple M on Wednesday the AFL had cracked down on dangerous tackles on doctors' advice.
"The reason why sling tackles is a focus is because we got medical advice that players with their arms pinned slammed into the turf is a real danger area - we’re seeing more shoulder injuries, collarbone, related to fierce tackling,” Anderson said.
“The thrust was, you need to protect the bloke who is tackled with his arms pinned."
The appeal will be heard at 5.30pm on Thursday, but Melbourne is able to name Trengove in its official team for this round to be lodged with the AFL at 4.30pm. He will be identified in the team "subject to appeal".
If the appeal is successful, the team lodged at 4.30pm becomes the official Melbourne 22, plus three emergencies, for round seven.
If the appeal is unsuccessful and some form of suspension is imposed, Melbourne must lodge its revised 22 with the AFL by 12 noon on Friday, without Trengove, who must be replaced by one of the three emergencies named in the team on Thursday night.
A new emergency player may also be named to replace the player now unable to be included in the 22-man team.
Luke Holmesby covers Melbourne news for afl.com.au. Follow him on Twitter: @AFL_LHolmesby.
