Damien Hardwick's young side was due to play the Indigenous All-Stars in Alice Springs earlier this month, but the match was cancelled due to wild weather caused by Cyclone Yasi.
The remaining four NAB Challenge matches, featuring the 10 teams eliminated in round one of the NAB Cup, will all be played on Saturday.
Greater Western Sydney will remain in the NAB Challenge series, and will front up in a twilight fixture against Carlton at Manuka Oval in Canberra on Saturday.
One young Giant may find himself lining up on reigning Brownlow medallist Chris Judd in his first match of the pre-season.
Hawthorn will take on North Melbourne at Skilled Stadium, the Western Bulldogs and Brisbane Lions will clash at Visy Park and Adelaide plays Fremantle at Thebarton Oval.
Match details: (local times shown)
Friday, 25th February
Port Adelaide vs Richmond Alice Springs 7.00pm
Saturday, 26th February
Hawthorn vs North Melbourne Skilled Stadium 1.00pm
Western Bulldogs vs Brisbane Lions Visy Park 1.00pm
Adelaide vs Fremantle Thebarton Oval (SA) 3.30pm
GWS Giants vs Carlton Manuka Oval 4.30pm