Each of the star trio, which combined to average more than 12 clearances a game last year, has missed a large portion of this season through serious injury, but coach Mark Harvey declared Mundy a 95 per cent chance to return from a high ankle injury at Etihad Stadium this week.
The 26-year-old has not played since round 12, with Sandilands, who has pulled up well from Saturday's loss to Carlton, playing just two games in that period. Barlow has played every game since round 17 after recovering from a broken leg.
Fremantle has won the clearance count just twice in its last 10 games - against Hawthorn and West Coast - and Carlton handed out a stoppage lesson to the ninth-placed team last Saturday, winning the indicator 43-25.
Harvey said he would unleash his big-name trio on the Kangaroos early on Saturday, as his team seeks to save its slim finals chances and arrest a four-game losing streak.
"We'll be going after them early, there's no question we'll be going after them," Harvey said from Fremantle Oval on Wednesday.
"In name, we'll be putting our best midfield forward so we'll have to manage it beyond that.
"As we know they probably need hit-outs, all of them, and in time hopefully they get a chance to prove that beyond the home and away season.
"It's very important to get off to a good start and make sure we can manipulate the situation.
"They (the Kangaroos) are coming off a break and I read that they've been refreshed and perhaps have looked at a few things, so we'll see what happens."
As a result of Fremantle's injury crisis this year, Harvey has introduced a host of new players into the midfield rotation, with Chris Mayne, Tendai Mzungu and Hayden Ballantyne all spending time in the centre against Carlton.
The coach said with close to his best team now available, he would move towards more familiar team structures against North Melbourne.
"What we've been able to do is to put players in different positions and elevate them into more serious roles," he said.
"Then with that comes some more scrutiny on players, perhaps before their time, because those guys have been out, so I think that'll hold us in good stead.
"I'm not sure whether Tendai has played with Aaron around the stoppages, so what happens is we put some different players in and around those areas and they're not au fait with some of Aaron's signals at times."
Captain Matthew Pavlich has been cleared of injury after feeling a "tweak" ahead of last Saturday's match and appearing hampered early in the game.
Harvey said the 29-year-old would still be required in the midfield for periods against North Melbourne, despite Mundy's return.
The coach also challenged third-year midfielder Stephen Hill to develop his on-field presence following comments from former teammate Des Headland that the speedster needed to demand more protection from his teammates.
"Part of evolving as a player is to not accept, or to be able to beat, what the opposition throw at you," Harvey said.
"There are different ways to do that. Des was basically talking about being a bit more verbal out on the ground.
"He's right. Stephen naturally is not an out-there extrovert, so he needs to evolve. It's part of his learning process."
