The Pies have lost two key defenders over the past two years, with James Clement retiring at the end of 2007 and Shane Wakelin pulling the pin last year.
With Brown, Harry O'Brien, Alan Toovey, Shannon Cox and Tyson Goldsack helping to make up the young backline, Prestigiacomo is the elder statesman in defence and has been taking the key forward this season.
Brown, 20, said Prestigiacomo's performance against big names such as Brendan Fevola and Warren Tredrea this year had really inspired the younger defenders.
"I'm really happy to be playing with Simon," he said.
"He's such a great player and person to be around, especially for myself personally and the team and the backline.
"He's got so much experience, and it comes across he's a really quiet bloke but he's just got so much wisdom to give to the team, especially to me."
The 31-year-old's future was in doubt last year after he missed more than half the season with a persistent foot injury.
This year, he has played every game – including his 200th league game in round five – and has put in some memorable performances such as his vice-like hold on Fevola in round eight that kept the Blue scoreless.
Brown said his ability to take on the competition's most potent goal-kickers this year had boosted the confidence of the younger backmen around him.
"He's playing so great, and to see him playing so great and stopping all these great forwards, it gives a young player like me so much more confidence to stop my player and play well," he said.
"I think it's sort of infectious amongst the team, and evident from the weekend."
