The superstar forward looms as the Crows biggest problem as they travel to the MCG to face the Hawks in next Saturday’s twilight preliminary final.
"That's a hard one, I've had a bit of a think about it this morning too, and I don't know if anyone can play on Buddy," Sanderson told Melbourne radio 3AW.
Click here to review the last time the Hawks and Crows met
"I don't know who in the competition is the best match up for Buddy, we'll certainly back our boys in this week."
Sanderson said injured Rising Star Daniel Talia would have been "perfect" for the role, but in his absence floated Ben Rutten as the likely man to be handed the challenge after his stand out role on Matthew Pavlich in the semi-final win.
Pavlich was kept to just 10 disposals and a single goal.
"Buddy's in a class of his own.
"He's an elite player. He's a really difficult match up cause he's got height but he's also got speed and agility," Sanderson said.
"You just can't let him have a possession inside 50 cause he'll make you pay.
"Once again we'll have to rely on pressure up the field, and we'll have a bit of a strategy meeting this week about how we can try and nullify him."
Matthew Jaensch and Andy Otten are potential replacements for Sam Shaw who suffered a hamstring injury in the first quarter.
Matt Thompson is a reporter for AFL Media. Follow him on Twitter @MattThompsonAFL