The Bombers have named 21 year-old Kyle Hardingham for his debut, while Bachar Houli and Leroy Jetta have also earned a call-up for Saturday night's match.
Jake Melksham and Nathan Lovett-Murray have been omitted, while Tom Bellchambers will miss with a foot injury.
Essendon
B: Heath Hocking, Cale Hooker, Dustin Fletcher
HB: Mark McVeigh, Michael Hurley, Courtenay Dempsey
C: Kyle Reimers, Jobe Watson, Travis Colyer
HF: David Zaharakis, Scott Gumbleton, Angus Monfries
F: Leroy Jetta, Jay Neagle, Sam Lonergan
Foll: Patrick Ryder, Jason Widerlich, Ben Howlett
I/C: Bachar Houli, Brent Stanton, Kyle Hardingham, Alwyn Davey
Emg: Brent Prismall, David Myers, Nathan Lovett-Murray
In: Houli, Jetta, Hardingham
Out: Jake Melksham, Nathan Lovett-Murray, Tom Bellchambers (foot)
New: Kyle Hardingham (East Fremantle)
