NORTH Melbourne coach Brad Scott has swung the selection axe, dropping four players for Sunday's clash with Carlton at Marvel Stadium.
Meanwhile, Adelaide has left Josh Jenkins in limbo, choosing not to recall the tall forward for a home meeting with Fremantle after two weeks in the SANFL.
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After announcing trade acquisition Aaron Hall was cut on Thursday, the Roos have omitted Sam Wright, Nathan Hrovat and Luke Davies-Uniacke.
Smooth-moving midfielder Shaun Higgins is back from illness, with Marley Williams (ankle), Taylor Garner and Jy Simpkin also returning.
The under-siege Kangaroos are facing a potential doomsday scenario against the Blues, who are also 1-5 and fell narrowly to Hawthorn in Launceston last round.
Carlton has lost some key personnel for the clash, with ruckman Matthew Kreuzer (adductor), Mitch McGovern (hamstring), Kade Simpson (hamstring) and Nic Newman (knee) all going out of the side.
Tall forward Charlie Curnow is a huge inclusion after a knee problem, with Andrew Phillips replacing Kreuzer, Tom Williamson called up and much-talked-about draftee Liam Stocker set for his debut.
Essendon has been boosted by Orazio Fantasia's return alongside Aaron Francis for a litmus test against the League-leading Cats at the MCG.
Mitch Brown misses through injury, while David Myers has been managed after the fighting loss to Collingwood on Anzac Day.
Geelong is coming off a thumping win over West Coast and has made just one change, bringing back rebounding defender Jordan Clark to replace another youngster, Charlie Constable.
Experienced Crows onballer Bryce Gibbs is back after a virus kept him out of the win over St Kilda, with Myles Poholke making way for the closing match to round seven at Adelaide Oval.
Jenkins' three goals and 18 disposals wasn't enough to force his way into a line-up which has shown signs of a rebirth against Gold Coast and the Saints.
But the Crows face a confident Fremantle side which will go in unchanged for the first time since round 21 last season.
The Dockers left Connor Blakely out of the 26-man squad after his comeback at WAFL level from a long-term hamstring, while Taylin Duman couldn't force his way back after coughing up his spot due to a one-game suspension.
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Friday, May 3
Collingwood v Port Adelaide at Marvel Stadium, 7.50pm AEST
COLLINGWOOD
In: B.Reid, J.Elliott
Out: M.Cox (ankle), T.Varcoe
PORT ADELAIDE
In: K.Amon
Out: R.Gray (hand)
Saturday, May 4
Melbourne v Hawthorn at the MCG, 1.45pm AEST
MELBOURNE
In: O.McDonald, J.Wagner, D.Keilty
Out: J.Viney (shoulder), S.Weideman, T.Smith (back soreness)
New: Declan Keilty (Casey)
HAWTHORN
In: D.Moore, S.Burgoyne
Out: J.Scrimshaw (managed), J.Cousins (suspension)
Greater Western Sydney v St Kilda at UNSW Canberra Oval, 1.45pm AEST
GREATER WESTERN SYDNEY
In: P.Davis, I.Cumming
Out: L.Whitfield (corked thigh), M.Buntine
ST KILDA
In: D.Joyce, J.Marsh, R.Marshall, H.Clark
Out: N.Brown, B.Longer, J.Lonie (knee), J.Steven (mental health)
New: Jonathon Marsh (Collingwood/East Fremantle)
Brisbane v Sydney at the Gabba, 4.35pm AEST
BRISBANE
No changes
SYDNEY
In: W.Hayward, K.Jack, R.Fox
Out: J.Rowbottom, R.Clarke, B.Ronke
Western Bulldogs v Richmond at Marvel Stadium, 7.25pm AEST
WESTERN BULLDOGS
No changes
RICHMOND
In: S.Bolton, C.Menadue
Out: J.Riewoldt (knee), D.Astbury (ankle)
West Coast v Gold Coast at Optus Stadium, 6.10pm AWST
WEST COAST
In: J.Redden
Out: J.Brander
GOLD COAST
In: A.Young, A.Miles, W.Powell
Out: P.Hanley (shin), W.Brodie, J.Lukosius
Sunday, May 5
Carlton v North Melbourne at Marvel Stadium, 1.10pm AEST
CARLTON
In: L.Stocker, C.Curnow, A.Phillips, T.Williamson
Out: K.Simpson (hamstring), M.McGovern (hamstring), M.Kreuzer (adductor), N.Newman (hamstring)
New: Liam Stocker (Sandringham U18)
NORTH MELBOURNE
In: S.Higgins, M.Williams, T.Garner, J.Simpkin
Out: A.Hall, S.Wright, N.Hrovat, L.Davies-Uniacke
Geelong v Essendon at the MCG, 3.20pm AEST
GEELONG
In: J.Clark
Out: C.Constable
ESSENDON
In: O.Fantasia, A.Francis
Out: M.Brown (hand), D.Myers (managed)
Adelaide v Fremantle at Adelaide Oval, 4.10pm ACST
ADELAIDE
In: B.Gibbs
Out: M.Poholke
FREMANTLE
Unchanged