But tough Lions tagger Chris Scott will face the tribunal next week after an ugly clash with Shane Crawford.
The Hawks have now lost four of their past five matches, after winning their first eight in a row.
Hawthorn came out fired up and booted the first two goals of the game, which was played in persistent rain, before the Lions went on a rampage, running out very impressive winners 20.20.140 to 8.5.53.
In front of a 30,573-strong crowd, the Lions midfield - led by Michael Voss, Jason Akermanis and Simon Black - gained a mountain of possession and guided Brisbane to victory.
The crushing win, which saw the Lions kick eight goals to a solitary major to the Hawks in the last quarter, was Brisbane's fourth in succession.
Lions forward Daniel Bradshaw came off the bench and kicked five goals and full forward Alastair Lynch three.
While Brisbane found scoring easy after a tight first quarter Hawthorn sorely missed in-form forward John Barker who was injured last weekend.
The lack of a focal point in front of goal was exploited by Lions fullback Mal Michael and back pocket Chris Johnson.
For Hawthorn, Jonathan Hay tried hard while captain Shane Crawford kicked two goals as did Aaron Lord.
More bad news for the Hawks was Daniel Chick being helped off the the ground in the dying minutes of the match.
The Hawks jumped the Lions in the first quarter with coach Peter Schwab using ruckmen Brett O'Farrell and Nathan Thompson in the centre square.
With possession football and tight defence the Hawks restricted the Lions to only one goal and kicked two themselves in the opening term.
In the second quarter the Lions broke free, booting six goals with the midfield exerting their dominance.
Scoreboard:
BRISBANE LIONS: 1.3, 7.8, 12.14, 20.20 (140)
HAWTHORN: 2.3, 4.5, 7.5, 8.5 (53)
Goals: Brisbane Lions: D Bradshaw 5 A Lynch 3 B Scott 2 J Brown 2 C McRae B McDonald C Johnson N Lappin S Black R Copeland M Voss J Akermanis. Hawthorn: S Crawford 2 A Lord 2 T Croad N Thompson D Chick D Harford.
Best: Brisbane Lions: M Voss J Akermanis C Johnson S Black M Michael N Lappin. Hawthorn: J Hay R Tallis B O'Farrell J Rawlings.
Umpires: B Sheehan C Rowe M James.
Official crowd: 30,573 at Gabba.
