Kerr, whose 2010 campaign ended in round four against Essendon when he tore a hamstring tendon off the bone, remains on a strict rehabilitation program less than three weeks before the Eagles' NAB Cup opener against Hawthorn and Fremantle.
Worsfold said the 27-year-old, who has played just 26 of 66 matches since being named an All-Australian in 2007, should be available to play late in the pre-season competition in an effort to prove his fitness ahead of the season opener.
"The plan at this stage is [that] he builds up his running and starts to incorporate kicking … and some more football activities over the next two to three weeks," Worsfold said from Claremont Oval on Wednesday.
"When he actually joins in with the players he'll be ready to go flat out; it's not as though he'll join in and have to build up for a couple of weeks.
"If he's up and training with the guys in three weeks, and he's at a pretty good fitness level, then give him three weeks of footy training and get him into it and he'd be then ready for practice games."
Worsfold said the premiership on-baller has been running at a good pace and getting plenty of volume into his training while working away from the main group.
Newly-appointed vice-captain Beau Waters, who will miss two weeks of pre-season training following a knee clean out, is the only other Eagle ruled out of the side's opening NAB Cup fixture against Fremantle and Hawthorn on February 13.
Nic Naitanui has been held back from high intensity ball-work because of hamstring tightness, but the ruck prodigy is set to re-join full training next Monday.
Worsfold said he was very pleased with the club's pre-season so far, particularly the form of draftees Andrew Gaff, Jack Darling and Scott Lycett, who are all likely to be unveiled in the NAB Cup opener.
"Really pleased with what they've all done … if they're up and going I'd say they'd get a run for sure," the coach said.
"In terms of the workload we've got into the players, that's well and truly on track.
"The attitude of the players is great [and] some of the improvement we've seen through a lot of the younger players has been really good as well."