The Croweaters 12.12 (84) defeated the Scorpions 8.5 (53).
Although South Australia led at each change, Queensland trailed by just 10 points at three-quarter -time, before the Croweaters booted four goals to one in the final term.
Highly-touted South Australian draft prospect Jack Trengove was one of the best with 18 disposals, five tackles and two goals in the midfield.
Luke Tapscott, another of South Australia's players to watch for in November, also impressed with 17 touches and nine inside-50s.
AIS/AFL academy graduate Alex Carey shone with a team-high 25 disposals for the Croweaters, while smalls Daniel Scott-Collings and Taite Silverlock chipped in with two majors.
Queensland skipper Marc Lock, who is not one of Gold Coast's contracted players, shone again with a match-best 29 disposals. Ruckman and contracted Gold Coast player Zac Smith dominated the ruck with 29 hit-outs.
Queensland 1.1 4.2 7.3 8.5 (53)
South Australia 4.3 5.5 8.7 12.12 (84)
GOALS
Queensland: Fowler 2, Bevan, Dixon, Lock, Magin, Manzone, Rees
South Australia: Scott-Collings 2, Silverlock 2, Trengove 2, Craig, Giddings, Hannath, Milera, Panos, Solly
BEST
Queensland: Thomas, Ramage, Magin, Lock, Grayson, Thomson, Smith
South Australia: Carey, Keller, Potts, Evans, Trengove, Panos, Menzel, Tapscott, Jolly
