Forward John Butcher was hospitalised with the infection last Thursday and was soon joined by injured ruckman Jarrad Redden.
The club underwent "a hospital-strength clean" and consulted the Communicable Disease branch of the South Australian Department of Health only to discover three new players from its SANFL Academy had become infected.
Both Butcher and Redden, the only two AFL-listed players to contract the illness, will remain quarantined from teammates and staff for at least another week.
The club's facilities are partially shared with the local community, which has made the location of the initial source of the infection difficult to identify.
The Power have ramped up the use of hand sanitizers and other common sense solutions to try and contain the outbreak, but won't introduce any further containment methods on Saturday night.
"The AFL is happy with the way Port has handled the outbreak and won’t be imposing any further guidelines or any other measures for Saturday night," a League spokesman said.
Twitter: @AFL_Harry